Topics

About our research

Our research focuses on the role of vascular disease in cognitive decline and dementia. This is referred to as vascular cognitive impairment (VCI). Cognition and dementia in people with type 2 diabetes has been a key topic. We have made important progress in determining the severity and course of development of cognitive decrements in diabetes and pre-diabetic stages and in identifying MRI correlates of impaired cognition. We also address other vascular risk factors for cognitive decline and dementia.

Our next targets are to make prediction models to identify patients at increased risk of VCI and to refine our brain imaging markers of vascular damage in these patients, also using high-resolution MRI at 7T. To this end we establish cohorts of patients that represent different aspects of VCI, in whom we collect detailed data on cognition and their vascular risk factor profile and obtain state of the art MRI scans.

Project description

See the contributions of the VCI Study Group to Alzheimer’s Association International Conference (AAIC) 2012
Please find more information on our research projects by clicking the following links:

  • 7T Alzheimer
  • COG-ID
  • Hippocampal subfields at 7T
  • Post-mortem MRI
  • Prisma adaption
  • PREDICT-MR
  • Prognosis in VCI
  • SMART-MR
  • UDES