Jacob-Jan Sloots

Jacob-Jan Sloots, Msc
PhD student

Applied Physics Bsc, Delft University of Technology
Biomedical Engineering Msc, Delft University of Technology

Research focus
MRI protocol development for Small Vessel Disease

Current projects
In his research, Jacob-Jan Sloots focusses on the development and application of an MRI method that is called DENSE (Displacement Encoding with Stimulated Echoes). This method measures brain tissue deformation, which could be a valuable source of information on the physiology of the brain. Brian tissue displacement is mainly driven by the heart. As blood flows into the brain’s vessels, the swell and stretch elastically, displacing the surrounding tissue. The figure below shows an example where brain tissue motion in the right-to-left direction is represented as a result of the cardiac output.
Currently, Jacob-Jan is working on a method to unravel brain tissue displacement induced by the cardiac and respiratory cycles.


E: j.j.sloots-2@umcutrecht.nl
T: +31 88 755 6866